Risk of Suicide Attempt in Poststroke Patients: A Population-Based Cohort Study

J Am Heart Assoc. 2018 Jan 10;7(2):e007830. doi: 10.1161/JAHA.117.007830.

Abstract

Background: This nationwide population-based cohort study evaluated the risk of and risk factors for suicide attempt in poststroke patients in Taiwan.

Methods and results: The poststroke and nonstroke cohorts consisted of 713 690 patients and 1 426 009 controls, respectively. Adults (aged >18 years) who received new stroke diagnoses according to the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM; codes 430-438) between 2000 and 2011 were included in the poststroke cohort. We calculated the adjusted hazard ratio for suicide attempt (ICD-9-CM codes E950-E959) after adjustment for age, sex, monthly income, urbanization level, occupation category, and various comorbidities. Kaplan-Meier analysis was used to measure the cumulative incidence of suicide attempt, and the Fine and Gray method was used as a competing event when estimating death subhazard ratios and 95% confidence intervals between groups. The cumulative incidence of suicide attempt was higher in the poststroke cohort, and the adjusted hazard ratio of suicide attempt was 2.20 (95% confidence interval, 2.04-2.37) compared with that of the controls. The leading risk factors for poststroke suicide attempt were earning low monthly income (<660 US dollars), living in less urbanized regions, doing manual labor, and having a stroke before age 50 years. The attempted suicide risk did not differ significantly between male and female patients in this study.

Conclusions: These results convey crucial information to clinicians and governments for preventing suicide attempt in poststroke patients in Taiwan and other Asian countries.

Keywords: National Health Insurance; cohort study; population studies; stroke; suicide.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age of Onset
  • Aged
  • Aged, 80 and over
  • Databases, Factual
  • Female
  • Humans
  • Income
  • Job Description
  • Male
  • Middle Aged
  • Occupations
  • Poverty
  • Residence Characteristics
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors
  • Social Determinants of Health
  • Stroke / diagnosis
  • Stroke / epidemiology*
  • Stroke / psychology*
  • Suicidal Ideation*
  • Suicide, Attempted / psychology*
  • Taiwan / epidemiology
  • Time Factors