KPC-2-producing Klebsiella pneumoniae ST11 in a Children's Hospital in Poland

Pol J Microbiol. 2017 Sep 27;66(3):401-404. doi: 10.5604/01.3001.0010.4884.

Abstract

Four Klebsiella pneumoniae isolates from children hospitalized over 10 months in an intensive care unit in a children's teaching hospital in Poland were analyzed. All of the isolates belonged to a single pulsotype and sequence type (ST) 11, and produced the KPC-2 carbapenemase and extended-spectrum β-lactamase (ESBL) CTX-M-15. They were resistant to a variety of antimicrobials, and their β-lactam resistance patterns were typical for KPC producers. This is one of few cases of identification of KPC (or carbapenemase)-producing K. pneumoniae in a pediatric center in Poland.

Keywords: KPC-2 producing K. pneumoniae ST11; carbapenemase; epidemiology.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Bacterial Typing Techniques
  • Child
  • Drug Resistance, Multiple, Bacterial / genetics*
  • Electrophoresis, Gel, Pulsed-Field
  • Female
  • Humans
  • Infant
  • Intensive Care Units, Pediatric
  • Klebsiella Infections / drug therapy
  • Klebsiella pneumoniae / drug effects
  • Klebsiella pneumoniae / genetics*
  • Klebsiella pneumoniae / isolation & purification*
  • Male
  • Microbial Sensitivity Tests
  • Poland
  • beta-Lactam Resistance / genetics*
  • beta-Lactamases / metabolism*

Substances

  • Anti-Bacterial Agents
  • beta-lactamase CTX-M-15
  • beta-lactamase KPC-2
  • beta-Lactamases