Visible-Light-Promoted Synthesis of 1,4-Dicarbonyl Compounds via Conjugate Addition of Aroyl Chlorides

Chao-Ming Wang; Dan Song; Peng-Ju Xia; Jing Wang; Hao-Yue Xiang; Hua Yang

doi:10.1002/asia.201701738

Visible-Light-Promoted Synthesis of 1,4-Dicarbonyl Compounds via Conjugate Addition of Aroyl Chlorides

Chem Asian J. 2018 Feb 2;13(3):271-274. doi: 10.1002/asia.201701738. Epub 2018 Jan 17.

Authors

Chao-Ming Wang¹, Dan Song¹, Peng-Ju Xia¹, Jing Wang¹, Hao-Yue Xiang¹, Hua Yang¹

Affiliation

¹ College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083, P. R. China.

PMID: 29316376
DOI: 10.1002/asia.201701738

Abstract

A facile visible-light photocatalytic conjugate addition to prepare 1,4-dicarbonyl compounds has been developed by employing readily available aroyl chlorides as aryl radical sources. This operationally simple method shows a broad scope with regard to both aroyl chlorides and Michael acceptors. As a result, a variety of 1,4-diketones were efficiently synthesized in moderate to good yields.

Keywords: 1,4-diketones; aroyl chlorides; conjugate addition; photocatalysis; radical reactions.