Exogenous Cushing syndrome due to misuse of potent topical steroid

Pediatr Dermatol. 2018 Mar;35(2):e121-e123. doi: 10.1111/pde.13409. Epub 2018 Jan 9.

Abstract

We report an infant with exogenous Cushing syndrome after being treated for 2 months with a potent topical corticosteroid via the mother's application of topical clobetasol for diaper rash without a prescription. We emphasize that potent topical steroids should be used with great caution, especially when used under occlusion (e.g., diaper area) and that parents should be warned about potential side effects of these medications, particularly when used in infants.

Keywords: corticosteroid; endocrine disorders; topical.

Publication types

  • Case Reports

MeSH terms

  • Administration, Topical
  • Clobetasol / administration & dosage
  • Clobetasol / adverse effects*
  • Cushing Syndrome / chemically induced*
  • Diaper Rash / drug therapy
  • Drug Misuse / adverse effects*
  • Female
  • Glucocorticoids / administration & dosage
  • Glucocorticoids / adverse effects*
  • Humans
  • Infant

Substances

  • Glucocorticoids
  • Clobetasol