Idelalisib rapidly improves platelet function tests in patients with chronic lymphocytic leukaemia

Br J Haematol. 2018 Dec;183(5):825-828. doi: 10.1111/bjh.15052. Epub 2018 Jan 7.

Authors

Gianluigi Reda¹, Ramona Cassin¹, Andrea Artoni², Bruno Fattizzo^{1

3}, Anna Lecchi², Silvia La Marca², Paolo Bucciarelli², Giorgia V Levati^{1

3}, Flora Peyvandi^{2

3}, Agostino Cortelezzi^{1

3}

Affiliations

¹ Haematology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico of Milan, Milan, Italy.
² A. Bianchi Bonomi Haemophilia and Thrombosis Centre, Fondazione IRCCS Ca' Granda Ospedale, Maggiore Policlinico of Milan, Milan, Italy.
³ University of Milan, Milan, Italy.

PMID: 29315493
DOI: 10.1111/bjh.15052

No abstract available

Keywords: aggregation test; bleeding; chronic lymphocytic leukaemia; idelalisib; platelets.

Publication types

Letter

MeSH terms

Adenosine Diphosphate / metabolism
Adenosine Triphosphate / metabolism
Aged
Aged, 80 and over
Antineoplastic Agents / therapeutic use*
Blood Platelets / chemistry
Blood Platelets / drug effects
Female
Humans
Leukemia, Lymphocytic, Chronic, B-Cell / drug therapy*
Male
Middle Aged
Platelet Aggregation / drug effects*
Platelet Function Tests
Purines / therapeutic use*
Quinazolinones / therapeutic use*

Substances

Antineoplastic Agents
Purines
Quinazolinones
Adenosine Diphosphate
Adenosine Triphosphate
idelalisib