EBUS: Faster, cheaper and most effective in lung cancer staging

Int J Clin Pract. 2018 Feb;72(2). doi: 10.1111/ijcp.13053. Epub 2018 Jan 3.

Abstract

The use of endobronchial ultrasound trans-bronchial needle aspiration (EBUS-TBNA) as the initial diagnostic and staging procedure in patients with suspected, non-metastatic lung cancer has gained substantial support, and is now recommended by numerous guidelines. Whereas considerable attention has been pointed to the reductions in costs achieved by EBUS-TBNA, that has not been the case for some of its more significant benefits, namely the reduction of the diagnostic work-up time and its ability to accurately assess and restage lymph nodes, which were previously stated incorrectly by CT or PET scan. Both these benefits translate into improved outcomes for patients, as delays are reduced, futile surgeries are prevented and curable operations can be performed on patients previously excluded by CT or PET scan. Indeed, the use of EBUS as the initial diagnostic and staging procedure has been proven to significantly increase survival, compared with conventional diagnostic and staging procedures, in a pragmatic, randomised controlled trial (Navani N. et al, 2015). The instalment of EBUS will have the greatest effect on overwhelmed, suboptimally functioning national healthcare systems, by decreasing the number of required diagnostic and staging procedures, therefore reducing both treatment delays and costs. The improved selection of surgical candidates by EBUS will result in improved patient outcomes. The latest findings regarding the benefits of EBUS are outlined in this review, which, to the best of our knowledge, is the first to emphasise the impact of the procedure, both on timing and costs of lung cancer staging, as well as on survival.

Publication types

  • Review

MeSH terms

  • Bronchi
  • Cost-Benefit Analysis
  • Endoscopic Ultrasound-Guided Fine Needle Aspiration* / economics
  • Endosonography
  • Health Care Costs*
  • Humans
  • Lung Neoplasms / diagnosis*
  • Lung Neoplasms / pathology*
  • Lymph Nodes / pathology*
  • Lymphatic Metastasis
  • Neoplasm Staging / economics
  • Neoplasm Staging / methods
  • Time Factors