Prevention of chronic rejection after lung transplantation

Anke Van Herck; Stijn E Verleden; Bart M Vanaudenaerde; Geert M Verleden; Robin Vos

doi:10.21037/jtd.2017.11.85

Prevention of chronic rejection after lung transplantation

J Thorac Dis. 2017 Dec;9(12):5472-5488. doi: 10.21037/jtd.2017.11.85.

Authors

Anke Van Herck^{1

2}, Stijn E Verleden², Bart M Vanaudenaerde², Geert M Verleden^{1

2}, Robin Vos^{1

2}

Affiliations

¹ Department of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium.
² Department of Chronic Diseases, Metabolism & Ageing (CHROMETA), Division of Respiratory Diseases, KU Leuven, Leuven, Belgium.

Abstract

Long-term survival after lung transplantation (LTx) is limited by chronic rejection (CR). Therapeutic strategies for CR have been largely unsuccessful, making prevention of CR an important and challenging therapeutic approach. In the current review, we will discuss current clinical evidence regarding prevention of CR after LTx.

Keywords: Chronic lung allograft dysfunction; lung transplantation (LTx); prevention; treatment.

Publication types

Review