Light rhythmic exercise with dietary milk fat globule membrane improves physical fitness in an elderly Japanese population: a double-blind randomized placebo-controlled trial

Biosci Biotechnol Biochem. 2018 Apr;82(4):677-682. doi: 10.1080/09168451.2017.1412248. Epub 2018 Jan 3.

Abstract

This study aimed to investigate the efficacy of home-based, light gymnastic exercise plus dietary milk fat globule membrane (MFGM) intake on physical fitness of an elderly Japanese sample in a pilot, double-blind, randomized, placebo-controlled trial. Seventy-one subjects (male, n = 13; female, n = 58) were randomly assigned into two groups: placebo (n = 35 [male, n = 6; female, n = 29]) and MFGM group (n = 36 [male, n = 7; female, n = 29]). The intervention was eight weeks. Subjects ingested either MFGM (1 g/day) or placebo tablets daily and engaged in an exercise program daily. Physical function tests were performed at baseline and after four and eight weeks. Foot tapping and open-close stepping scores significantly increased from baseline to eight weeks in the MFGM group. Study results suggest daily MFGM ingestion might further enhance the effects of light-intensity exercise in healthy elderly people.

Keywords: Aging; gymnastic exercise; life expectancy; milk fat globule membrane; physical fitness.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Asian People*
  • Dietary Fats / administration & dosage*
  • Dietary Proteins / administration & dosage*
  • Double-Blind Method
  • Exercise Test
  • Female
  • Glycolipids / administration & dosage*
  • Glycoproteins / administration & dosage*
  • Gymnastics*
  • Humans
  • Japan
  • Lipid Droplets
  • Male
  • Muscle, Skeletal / physiology
  • Physical Fitness*
  • Pilot Projects
  • Placebos

Substances

  • Dietary Fats
  • Dietary Proteins
  • Glycolipids
  • Glycoproteins
  • Placebos
  • milk fat globule