Alternative strategies for vaccination to brucellosis

Microbes Infect. 2018 Oct-Nov;20(9-10):599-605. doi: 10.1016/j.micinf.2017.12.006. Epub 2017 Dec 26.

Abstract

Brucellosis remains burdensome for livestock and humans worldwide. Better vaccines for protection are needed to reduce disease incidence. Immunity to brucellosis and barriers to protection are discussed. The benefits and limitations of conventional and experimental brucellosis vaccines are outlined, and novel vaccination strategies needed to ultimately protect against brucellosis are introduced.

Keywords: Bacteria; Mucosal immunity; Vaccine.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Administration, Mucosal
  • Animals
  • Brucella Vaccine / administration & dosage*
  • Brucella Vaccine / immunology
  • Brucellosis / immunology
  • Brucellosis / prevention & control*
  • Brucellosis / veterinary*
  • Humans
  • Immunity, Cellular
  • Vaccination / trends
  • Vaccination / veterinary*

Substances

  • Brucella Vaccine