Generating the Abscopal Effect by Combining Proapoptotic Peptides With IL-12-Based Immunotherapy

Neoplasia. 2018 Feb;20(2):193-196. doi: 10.1016/j.neo.2017.11.009. Epub 2017 Dec 26.

Authors

Filipe Martins¹, Grégoire Stalder¹, Michel Obeid²

Affiliations

¹ Centre hospitalier universitaire vaudois (CHUV), Service et laboratoire central d'hématologie, département d'oncologie, rue du Bugnon 46, CH-1011 Lausanne, Switzerland.
² Centre hospitalier universitaire vaudois (CHUV), Centre d'immunothérapie et de la vaccinologie, rue du Bugnon 17, CH-1011 Lausanne, Switzerland; Université Pierre et Marie Curie, Faculté de Médecine Pitié-Salpêtrière, Centre Hospitalo-Universitaire Pitié-Salpêtrière, 91 Boulevard de l'Hôpital, F-75013 Paris, France. Electronic address: michel.obeid@chuv.ch.

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Apoptosis
Cell Proliferation
Colonic Neoplasms / immunology
Colonic Neoplasms / pathology
Colonic Neoplasms / therapy*
Drug Therapy, Combination
Female
Humans
Immunotherapy*
Interleukin-12 / immunology*
Interleukin-12 / metabolism
Mice
Mice, Inbred BALB C
Mice, Nude
Peptide Fragments / administration & dosage*
Peptide Fragments / immunology
Peptide Fragments / metabolism
Tumor Cells, Cultured
Xenograft Model Antitumor Assays

Substances

Peptide Fragments
Interleukin-12