Cardiac function and dysfunction in the fetus

Echocardiography. 2017 Dec;34(12):1776-1787. doi: 10.1111/echo.13654.

Abstract

Evaluation of fetal cardiac function is one of the most important components of fetal echocardiography. Fetal cardiac dysfunction is closely linked to risk of intrauterine fetal demise, in many, but not all cases is indicative of worse postnatal prognosis and may prompt the use of medications or interventions to optimize outcomes. There may be implications for termination versus continuation of pregnancy, an indication for early delivery, a change in location and even mode of delivery. In extreme cases, fetal cardiac dysfunction may prompt prenatal or early neonatal listing for cardiac transplantation. There are several important differences between the fetal and postnatal circulatory physiology which affect echocardiographic assessment of cardiac dysfunction. In this review, we examine the echocardiographic findings according to their underlying pathophysiology with reference to common causes.

Keywords: diastolic function; fetal echocardiography; systolic function.

Publication types

  • Review

MeSH terms

  • Echocardiography / methods*
  • Female
  • Fetal Heart / diagnostic imaging*
  • Fetal Heart / physiology*
  • Fetal Heart / physiopathology
  • Heart Defects, Congenital / diagnostic imaging*
  • Heart Defects, Congenital / physiopathology*
  • Humans
  • Pregnancy
  • Ultrasonography, Prenatal / methods*