Applications of Virus Vector-Mediated Gene Therapy in China

Hum Gene Ther. 2018 Feb;29(2):98-109. doi: 10.1089/hum.2017.238.

Abstract

Due to the increased safety and efficiency of virus vectors, virus vector-mediated gene therapy is now widely used for various diseases, including monogenic diseases, complex disorders, and infectious diseases. Recent gene therapy trials have shown significant therapeutic benefits, and Chinese researchers have contributed significantly to this progress. This review highlights disease applications and strategies for virus vector-mediated gene therapy in preclinical studies and clinical trials in China.

Keywords: China; cancer; clinical trial; gene therapy; liver disease; viral vector.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • China
  • Gene Transfer Techniques / trends*
  • Genetic Therapy / trends*
  • Genetic Vectors / therapeutic use*
  • Humans
  • Viruses / genetics*