A Photoinduced Reversible Phase Transition in a Dipeptide Supramolecular Assembly

Abstract

Tunable supramolecular assembly has found various applications in biomedicine, molecular catalysis, optoelectronics, and nanofabrication. Unlike traditional covalent conjugation, non-covalent introduction of a photoswitchable moiety enables reversible photomodulation of non-photosensitive dipeptide supramolecular assembly. Under light illumination, a long-lived photoacid generator releases a proton and mediates the dissociation of dipeptide-based organogel, thereby resulting in sol formation. Under darkness, the photoswitchable moiety entraps a proton, resulting in gel regeneration. Furthermore, accompanying the isothermal recycled gel-sol transition in a spatially controlled manner, renewable patterns are spontaneously fabricated. This new concept of light-controlled phase transition of amino acid-based supramolecular assemblies will open up the possibility of wide applications.

Keywords: dipeptides; phase transition; photoacid generators; photoswitches; supermolecular assembly.