An Evaluation of Clinical Economics and Cases of Cost-effectiveness

Intern Med. 2018 May 1;57(9):1191-1200. doi: 10.2169/internalmedicine.9835-17. Epub 2017 Dec 27.

Abstract

In order to maintain and develop a universal health insurance system, it is crucial to utilize limited medical resources effectively. In this context, considerations are underway to introduce health technology assessments (HTAs), such as cost-effectiveness analyses (CEAs), into the medical treatment fee system. CEAs, which is the general term for these methods, are classified into four categories, such as cost-effectiveness analyses based on performance indicators, and in the comparison of health technologies, the incremental cost-effectiveness ratio (ICER) is also applied. When I comprehensively consider several Japanese studies based on these concepts, I find that, in the results of the analysis of the economic performance of healthcare systems, Japan shows the most promising trend in the world. In addition, there is research indicating the superior cost-effectiveness of Rituximab against refractory nephrotic syndrome, and it is expected that health economics will be actively applied to the valuation of technical innovations such as drug discovery.

Keywords: QALY; cost-effectiveness analysis; health technology assessments; kidney failure; nephrotic syndrome; value of healthcare.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents, Immunological / economics
  • Antineoplastic Agents, Immunological / therapeutic use
  • Cost-Benefit Analysis / organization & administration*
  • Economics*
  • Humans
  • Japan
  • Nephrotic Syndrome / drug therapy
  • Rituximab / economics
  • Rituximab / therapeutic use
  • Technology Assessment, Biomedical / organization & administration*

Substances

  • Antineoplastic Agents, Immunological
  • Rituximab