Drug-induced Pressure Ulcers in a Middle-aged Patient with Early-stage Parkinson's Disease

Intern Med. 2018 May 15;57(10):1483-1486. doi: 10.2169/internalmedicine.9700-17. Epub 2017 Dec 27.

Abstract

Drug-induced pressure ulcer (DIPU), which is a newly recognized adverse drug reaction, is associated with the administration of psychiatric drugs in geriatric patients with dementia. The notification of the causative drugs is crucial to the treatment of DIPU. We herein report the case of a 56-year-old woman with early-stage Parkinson's disease who developed DIPUs after starting olanzapine treatment for depressive symptoms. Our findings illustrate that if an akinetic patient with pressure ulcers is encountered, the patient's medication should be reviewed by a multidisciplinary team, to evaluate whether the development of the pressure ulcer is drug-related, regardless of the patient's age.

Keywords: Parkinson's disease; adverse drug reaction; drug-induced parkinsonism; drug-induced pressure ulcer; pressure ulcer; psychiatric drug.

Publication types

  • Case Reports

MeSH terms

  • Antipsychotic Agents / adverse effects*
  • Benzodiazepines / adverse effects*
  • Depression / drug therapy*
  • Female
  • Humans
  • Middle Aged
  • Olanzapine
  • Parkinson Disease / psychology*
  • Pressure Ulcer / chemically induced*

Substances

  • Antipsychotic Agents
  • Benzodiazepines
  • Olanzapine