Radiation Pneumonitis with Eosinophilic Alveolitis in a Lung Cancer Patient

Intern Med. 2018 May 1;57(9):1281-1285. doi: 10.2169/internalmedicine.9338-17. Epub 2017 Dec 27.

Abstract

A 59-year-old woman suffering from dry cough and dyspnea was admitted to our hospital. She had undergone concurrent chemo-radiotherapy five months earlier. Chest computed tomography revealed bilateral ground-glass opacities extending outside the irradiated lung field. Her eosinophil numbers were increased in both the peripheral blood and the bronchoalveolar lavage fluid; therefore, she was diagnosed with radiation pneumonitis accompanied by eosinophilic alveolitis. Steroid therapy promptly improved the pneumonitis. Radiation pneumonitis accompanied by eosinophilic alveolitis extending outside the irradiated field is rare. Bronchoalveolar lavage is useful for a diagnosis, and steroid therapy is effective for treatment.

Keywords: bronchoalveolar lavage; eosinophilia; lung cancer; radiation pneumonitis; steroid.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use*
  • Alveolitis, Extrinsic Allergic / diagnostic imaging
  • Alveolitis, Extrinsic Allergic / drug therapy*
  • Alveolitis, Extrinsic Allergic / etiology*
  • Eosinophils / pathology
  • Female
  • Humans
  • Lung / pathology
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / radiotherapy*
  • Middle Aged
  • Radiation Pneumonitis / diagnostic imaging
  • Radiation Pneumonitis / drug therapy*
  • Radiation Pneumonitis / etiology*
  • Radiotherapy / adverse effects*
  • Treatment Outcome

Substances

  • Adrenal Cortex Hormones