Complications with cement spacers in 2-stage treatment of periprosthetic joint infection on total hip replacement

Orthop Traumatol Surg Res. 2018 May;104(3):333-339. doi: 10.1016/j.otsr.2017.11.016. Epub 2017 Dec 23.

Abstract

Introduction: The aim of the present study was to assess our management of infected total hip replacement in indications for 2-stage surgical treatment according to current guidelines when a cement spacer has been used. The study hypothesis was that the complications rate related to cement spacers is low.

Material and method: A single-center retrospective study included 26 patients receiving a spacer between the two stages of total hip replacement, over a 5 year period. We analyzed the spacers used, mechanical complications, infectious complications and the second stage of surgery.

Results: During the interval between surgeries, in the 26 patients, there were 19 spacer-related mechanical complications (73% of patients): 11 dislocations (42.3%), 5 spacer fractures (19.2%), 5 femoral bone lyses or fractures (19.2%) and 3 acetabular lyses or fractures (11.5%). In 4 cases, complications were associated. The greater the femoral offset of the spacer, the more frequent were femoral bone lyses or fractures (p=0.05), and the smaller the offset the more frequent were acetabular lyses or fractures (p=0.05). The rates of mechanical complications (p=0.003) and spacer fracture (p=0.02) were significantly greater in older patients. There were 4 cases of reinfection (19%): i.e., an 81% treatment success rate. One reinfection implicated a new bacterium: methicillin-susceptible Staphylococcus aureus. The second surgical stage was significantly longer in complex bipolar revision (p=0.009).

Conclusion: The present results showed a high risk of spacer-related complications, and thus the importance of selection of patients liable to derive real benefit and those for whom a Gilderstone procedure would be preferable.

Level of evidence: IV, retrospective study.

Keywords: Bone and joint infection; Complications; Side-effects; Spacer; Total hip replacement.

Publication types

  • Observational Study

MeSH terms

  • Acetabulum / injuries
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Arthritis, Infectious / surgery
  • Arthroplasty, Replacement, Hip / adverse effects*
  • Arthroplasty, Replacement, Hip / instrumentation*
  • Arthroplasty, Replacement, Hip / methods
  • Bone Cements / adverse effects*
  • Female
  • Femoral Fractures / etiology
  • Hip Dislocation / etiology
  • Humans
  • Male
  • Osteolysis / etiology
  • Prosthesis Failure / etiology
  • Prosthesis-Related Infections / etiology*
  • Prosthesis-Related Infections / surgery*
  • Reoperation
  • Retrospective Studies
  • Treatment Outcome

Substances

  • Bone Cements