Improved Photophysical and Photochemical Properties of Thiopheneethoxy Substituted Metallophthalocyanines on Immobilization onto Gold-speckled Silica Nanoparticles

Edith Dube; David O Oluwole; Tebello Nyokong

doi:10.1111/php.12879

Improved Photophysical and Photochemical Properties of Thiopheneethoxy Substituted Metallophthalocyanines on Immobilization onto Gold-speckled Silica Nanoparticles

Photochem Photobiol. 2018 May;94(3):521-531. doi: 10.1111/php.12879. Epub 2018 Mar 25.

Authors

Edith Dube¹, David O Oluwole¹, Tebello Nyokong¹

Affiliation

¹ Department of Chemistry, Center for Nanotechnology Innovation, Rhodes University, Grahamstown, South Africa.

PMID: 29274109
DOI: 10.1111/php.12879

Abstract

This work reports on the synthesis of tetrakis-[(thiophineethoxy) phthalocyaninato] indium(II) chloride (3). The photophysical behavior of complex 3 was compared to that of the Zn derivative (tetrakis-[(thiophineethoxy) phthalocyaninato] zinc(II) (complex 2)). The compounds were interacted with gold-speckled silica (GSS) nanoparticles via Au-S self assembly to afford the conjugates (2-GSS and 3-GSS). The photophysicochemical behavior of the compounds and their conjugates were assessed. The conjugates afforded a decrease in fluorescence quantum yields and lifetimes with improved triplet and singlet oxygen quantum yields in comparison with complexes 2 and 3 alone. The complexes and their conjugates could serve as good candidates for photodynamic therapy.

Publication types

Research Support, Non-U.S. Gov't