Association of postprocedural aortic regurgitation with mitral regurgitation worsened after transcatheter aortic valve replacement

Echocardiography. 2018 Mar;35(3):346-352. doi: 10.1111/echo.13780. Epub 2017 Dec 22.

Abstract

Background: There is a paucity of investigation which demonstrates a predictor of mitral regurgitation (MR) worsened after aortic valve replacement (TAVR).

Aim: The aim of this study was to identify the predictor of worsened MR after transcatheter TAVR.

Methods: We retrospectively studied a total of 209 patients with mild or less MR at baseline who underwent TAVR for the treatment of severe aortic stenosis with the balloon-expandable device. We found the presence of MR worsened after TAVR in 6% (12 patients) of all patients. Moderate or more postprocedural aortic regurgitation (AR) (odds ratio, 8.104; 95% confidence interval, 1.78-36.87; P = .007) was identified as a predictor of MR worsening after TAVR. In-hospital outcomes indicated that patients within whom MR worsened suffered congestive heart failure more than those with unchanged or improved MR after TAVR (P < .05).

Conclusion: Significant postprocedural AR was associated with MR worsened from mild or less to moderate or more after TAVR. Worsened MR might affect in-hospital congestive heart failure.

Keywords: aortic stenosis; echocardiography; valvular heart disease.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aortic Valve / diagnostic imaging
  • Aortic Valve / physiopathology
  • Aortic Valve Insufficiency / complications*
  • Aortic Valve Insufficiency / diagnostic imaging*
  • Aortic Valve Insufficiency / physiopathology
  • Echocardiography / methods
  • Female
  • Humans
  • Male
  • Mitral Valve / diagnostic imaging
  • Mitral Valve / physiopathology
  • Mitral Valve Insufficiency / complications*
  • Mitral Valve Insufficiency / diagnostic imaging*
  • Mitral Valve Insufficiency / physiopathology
  • Postoperative Complications / diagnostic imaging*
  • Postoperative Complications / physiopathology
  • Retrospective Studies
  • Severity of Illness Index
  • Transcatheter Aortic Valve Replacement*
  • Treatment Outcome