[Structure-activity relationship of plant polysaccharides]

Abstract

Plant polysaccharides have a variety of biological activities and have become the focus of many fields such as the areas of medicine and food for the features of safety, high efficiency and low toxicity. The chemical structure of plant polysaccharides is the foundation for the biological activity. Polysaccharides with different chemical structures have great differences in biological activity. The exploration of the structure-activity relationship of plant polysaccharides has guiding significance for the development of new drugs and the health care products of saccharides. Many biological activities of plant polysaccharides such as anti-hepatic injury, antineoplastic, antiviral, hypoglycemia, anticoagulation, anti-oxidation and immunoregulation have been discovered. Therefore, this paper focuses on the bioactivity as the main line, and summarizes the studies on structure-activity relationship and mechanism of plant polysaccharides at home and abroad in recent years. The key point is the structure-activity relationship between plant polysaccharides and the anti-hepatic injury, antineoplastic, antiviral, hypoglycemia, and anticoagulation activities, providing reference for intensive study and exploration of structure-activity relationship of plant polysaccharides as well as development and application of polysaccharides products.

Keywords: biological activity; mechanism of action; plant polysaccharides; structure-activity relationship.