Management of Ebola Virus Disease in Children

Indi Trehan; Stephanie C De Silva

doi:10.1016/j.idc.2017.10.010

Management of Ebola Virus Disease in Children

Infect Dis Clin North Am. 2018 Mar;32(1):201-214. doi: 10.1016/j.idc.2017.10.010. Epub 2017 Dec 18.

Authors

Indi Trehan¹, Stephanie C De Silva²

Affiliations

¹ Lao Friends Hospital for Children, Luang Prabang, Lao PDR; Department of Pediatrics, One Children's Place, Campus Box 8116, St Louis, MO 63110, USA; Maforki Ebola Holding and Treatment Centre, Port Loko, Sierra Leone. Electronic address: indi@alum.berkeley.edu.
² Department of Pediatrics, One Children's Place, Campus Box 8116, St Louis, MO 63110, USA.

PMID: 29269191
DOI: 10.1016/j.idc.2017.10.010

Abstract

The West African outbreak of 2013 to 2016 was the largest Ebola epidemic in history. With tens of thousands of patients treated during this outbreak, much was learned about how to optimize clinical care for children with Ebola. In anticipation of inevitable future outbreaks, a firsthand summary of the major aspects of pediatric Ebola case management in austere settings is presented. Emphasis is on early and aggressive critical care, including fluid resuscitation, electrolyte repletion, antimicrobial therapy, and nutritional supplementation.

Keywords: Children; Clinical management; Critical care; Diagnosis; Ebola; Pediatrics; Screening; Therapy.

Publication types

Review

MeSH terms

Child
Critical Care
Disease Management*
Disease Outbreaks / prevention & control
Epidemics / prevention & control
Fluid Therapy
Health Personnel
Hemorrhagic Fever, Ebola / diagnosis*
Hemorrhagic Fever, Ebola / epidemiology
Hemorrhagic Fever, Ebola / prevention & control
Hemorrhagic Fever, Ebola / therapy*
Humans
Post-Exposure Prophylaxis
Tropical Climate