Pediatric Community-Acquired Pneumonia in the United States: Changing Epidemiology, Diagnostic and Therapeutic Challenges, and Areas for Future Research

Infect Dis Clin North Am. 2018 Mar;32(1):47-63. doi: 10.1016/j.idc.2017.11.002. Epub 2017 Dec 18.

Abstract

Community-acquired pneumonia (CAP) is one of the most common serious infections in childhood. This review focuses on pediatric CAP in the United States and other industrialized nations, specifically highlighting the changing epidemiology of CAP, diagnostic and therapeutic challenges, and areas for further research.

Keywords: Community-acquired pneumonia; Epidemiology; Pediatric.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Biomarkers
  • Child
  • Community-Acquired Infections / diagnosis*
  • Community-Acquired Infections / drug therapy
  • Community-Acquired Infections / epidemiology*
  • Host-Pathogen Interactions / genetics
  • Humans
  • Molecular Diagnostic Techniques
  • Pneumococcal Infections / drug therapy
  • Pneumococcal Infections / epidemiology
  • Pneumococcal Infections / prevention & control
  • Pneumococcal Vaccines / administration & dosage
  • Pneumonia / diagnosis*
  • Pneumonia / drug therapy
  • Pneumonia / epidemiology*
  • Pneumonia / etiology
  • Streptococcus pneumoniae / drug effects
  • Streptococcus pneumoniae / genetics
  • Streptococcus pneumoniae / isolation & purification
  • Streptococcus pneumoniae / pathogenicity
  • United States / epidemiology

Substances

  • Anti-Bacterial Agents
  • Biomarkers
  • Pneumococcal Vaccines