Diffuse Idiopathic Hyperostosis Manifesting as Dysphagia and Bilateral Cord Paralysis: A Case Report and Literature Review

World Neurosurg. 2018 Mar:111:79-85. doi: 10.1016/j.wneu.2017.12.063. Epub 2017 Dec 18.

Abstract

Background: Diffuse idiopathic hyperostosis (DISH) is characterized by calcifications affecting mainly the spinal anterior longitudinal ligament. This disease is mainly asymptomatic but cervical osteophytes can sometimes cause dysphagia (DISHphagia), hoarseness, and even dyspnea.

Case description: We report, for the first time in the medical literature, a case of a 76-year-old patient with DISH causing an important dysphagia as well as bilateral vocal cord paralysis causing critical dyspnea. The patient was surgically treated by anterior resection of the osteophytes and application of bone wax, with significant clinical improvement and no radiologic recurrence after 2 years of follow-up.

Discussion and conclusion: A thorough literature review didn't yield any article reporting on bilateral vocal cord paralysis caused by DISH. Management of this condition is typically multidisciplinary, and treatment of cervical osteophyte-associated dysphagia or respiratory compromise is primarily medical, after performing necessary tests to rule out other causes of dysphagia. Surgical intervention is warranted when medical treatment fails, when there is weight loss, a significant airway compromise or sleeping alterations. A treatment algorithm is proposed in the end of this review for symptomatic anterior osteophytes caused by DISH in the mobile cervical spine.

Keywords: Diffuse idiopathic hyperostosis; Dysphagia; Vocal cord paralysis.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Bone Substitutes
  • Deglutition Disorders / diagnostic imaging
  • Deglutition Disorders / etiology*
  • Deglutition Disorders / surgery
  • Humans
  • Hyperostosis, Diffuse Idiopathic Skeletal / complications*
  • Hyperostosis, Diffuse Idiopathic Skeletal / diagnostic imaging
  • Hyperostosis, Diffuse Idiopathic Skeletal / surgery
  • Male
  • Osteophyte / surgery
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Vocal Cord Paralysis / diagnostic imaging
  • Vocal Cord Paralysis / etiology*
  • Vocal Cord Paralysis / surgery

Substances

  • Bone Substitutes