Specific changes of enteric mycobiota and virome in inflammatory bowel disease

J Dig Dis. 2018 Jan;19(1):2-7. doi: 10.1111/1751-2980.12570.

Abstract

One of the important features of inflammatory bowel disease (IBD) is dysbiosis of the gut microbiota. It has been well documented that changes in the commensal bacterial population are involved in IBD development. However, the function of the fungal and viral communities in IBD remains unclear. Moreover, the optimal treatment for IBD patients with opportunistic infections is still undecided. This review focused on how the enteric mycobiota and virome changes during the pathogenesis of IBD and discussed potential treatment strategies that open new insights into the managements of IBD.

Keywords: dysbiosis; inflammatory bowel diseases; mycobiota; virome.

Publication types

  • Review

MeSH terms

  • Dysbiosis / microbiology
  • Dysbiosis / virology
  • Gastrointestinal Microbiome*
  • Gastrointestinal Tract / virology
  • Humans
  • Inflammatory Bowel Diseases / microbiology*
  • Inflammatory Bowel Diseases / virology
  • Viruses / isolation & purification*