Data on the expression and role of TREM-1 in the development of in-stent restenosis

Fang Wang; Chang Li; Feng Hua Ding; Ying Shen; Jie Gao; Zhu Hui Liu; Jia Wei Chen; Rui Yan Zhang; Wei Feng Shen; Xiao Qun Wang; Lin Lu

doi:10.1016/j.dib.2017.11.065

Data on the expression and role of TREM-1 in the development of in-stent restenosis

Data Brief. 2017 Nov 22:16:604-607. doi: 10.1016/j.dib.2017.11.065. eCollection 2018 Feb.

Authors

Fang Wang¹, Chang Li¹, Feng Hua Ding¹, Ying Shen¹, Jie Gao¹, Zhu Hui Liu², Jia Wei Chen², Rui Yan Zhang¹, Wei Feng Shen^{1

2}, Xiao Qun Wang^{1

2}, Lin Lu^{1

2}

Affiliations

¹ Department of Cardiology, RuiJin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, PR China.
² Institute of Cardiovascular Diseases, Shanghai Jiao-Tong University School of Medicine, Shanghai, PR China.

Abstract

The data presented in this article are related to the research article entitled "Increased serum TREM-1 level is associated with in-stent restenosis, and activation of TREM-1 promotes inflammation, proliferation and migration in vascular smooth muscle cells" (Wang et al., 2017) [1], which demonstrated that TREM-1 is expressed on vascular smooth cells (VSMCs) and promotes inflammation, proliferation and migration in cultured VSMCs. In this dataset, the expression of TREM-1 in leukocytes and endothelial cells of carotid artery after ligation was evaluated. The effect of TREM-1 on stenosis was analyzed in cultured human saphenous veins (HSVs) that spontaneously undergo remodeling which involves VSMC proliferation and migration.