Inner filter effect-based fluorescent sensing systems: A review

Shuai Chen; Yong-Liang Yu; Jian-Hua Wang

doi:10.1016/j.aca.2017.10.026

Inner filter effect-based fluorescent sensing systems: A review

Anal Chim Acta. 2018 Jan 25:999:13-26. doi: 10.1016/j.aca.2017.10.026. Epub 2017 Oct 27.

Authors

Shuai Chen¹, Yong-Liang Yu², Jian-Hua Wang³

Affiliations

¹ College of Life and Health Sciences, Northeastern University, Shenyang 110169, China.
² Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Box 332, Shenyang 110819, China. Electronic address: yuyl@mail.neu.edu.cn.
³ Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Box 332, Shenyang 110819, China.

PMID: 29254563
DOI: 10.1016/j.aca.2017.10.026

Abstract

Inner filter effect (IFE) was previously considered as an error in fluorescence measurement. In recent years, it has been developed as an important non-irradiation energy conversion model of spectroscopic technique and found wide applications in the fields of chemical sensing and biosensing. In comparison with traditional techniques based on forster resonance energy transfer (FRET), the IFE-based fluorescent approach is more flexible and straightforward without the link of absorber with fluorescer. The present review for the first time introduces the state of the art in the progress of the IFE-based fluorescent sensing systems, including sensing strategy, essential conditions, materials option, and their applications for the detection of various target analytes, e.g., ionic species, small molecules, and macromolecules. In addition, the benefits and limitations of the IFE-based fluorescent sensing systems are also critically discussed and highlighted.

Keywords: Fluorescence; Inner filter effect; Sensing application; Spectroscopic technique.

Publication types

Review