Absence of MGMT promoter methylation in diffuse midline glioma, H3 K27M-mutant

Acta Neuropathol Commun. 2017 Dec 15;5(1):98. doi: 10.1186/s40478-017-0500-2.

Authors

Rouzbeh Banan¹, Arne Christians¹, Stephan Bartels², Ulrich Lehmann², Christian Hartmann³

Affiliations

¹ Institute of Pathology, Department of Neuropathology, Hannover Medical School (MHH), Carl-Neuberg-Str. 1, D-30625, Hannover, Germany.
² Institute of Pathology, Hannover Medical School, Hannover, Germany.
³ Institute of Pathology, Department of Neuropathology, Hannover Medical School (MHH), Carl-Neuberg-Str. 1, D-30625, Hannover, Germany. hartmann.christian@mh-hannover.de.

No abstract available

Keywords: Diffuse midline glioma H3 K27M-mutant; H3F3A; HIST1H3B; MGMT.

Publication types

Letter

MeSH terms

Adolescent
Adult
Aged
Brain Neoplasms / genetics*
Child
Child, Preschool
DNA Methylation / genetics*
DNA Modification Methylases / genetics*
DNA Repair Enzymes / genetics*
Female
Glioma / genetics*
Histones / genetics*
Humans
Infant
Male
Middle Aged
Promoter Regions, Genetic / genetics*
Retrospective Studies
Tumor Suppressor Proteins / genetics*
Young Adult

Substances

H3-3A protein, human
Histones
Tumor Suppressor Proteins
DNA Modification Methylases
MGMT protein, human
DNA Repair Enzymes