Broadband 19F TOCSY using BURBOP-based spin lock

Alexander A Marchione; Elizabeth L Diaz

doi:10.1016/j.jmr.2017.12.002

Broadband ¹⁹F TOCSY using BURBOP-based spin lock

J Magn Reson. 2018 Jan:286:143-147. doi: 10.1016/j.jmr.2017.12.002. Epub 2017 Dec 5.

Authors

Alexander A Marchione¹, Elizabeth L Diaz²

Affiliations

¹ Chemours Fluoroproducts Analytical, Wilmington, DE, USA. Electronic address: alexander.marchione@chemours.com.
² Chemours Fluoroproducts Analytical, Wilmington, DE, USA.

PMID: 29245080
DOI: 10.1016/j.jmr.2017.12.002

Abstract

A train of BURBOP universal rotation pulses has been used to generate a spin lock sufficient to observe TOCSY correlations over a 46 kHz ¹⁹F spectral window (i.e. 122 ppm on a 9.4 T spectrometer). This spin lock requires lower RF field (γB₁ = 15 kHz), and was employed over a wider spectral window, than previously reported DIPSI-2 spin locks. The BURBOP-based spin lock was effected for 80-160 ms periods with a 2% duty cycle without evidence of harm to the RF coil of the probehead. Spectral separation and full set of correlations were obtained for a mixture of perfluorocarbons.

Keywords: (19)F; BURBOP; Spin lock; TOCSY.