Chemically synthesized histone H2A Lys13 di-ubiquitination promotes binding of 53BP1 to nucleosomes

Cell Res. 2018 Feb;28(2):257-260. doi: 10.1038/cr.2017.157. Epub 2017 Dec 15.

Authors

Jia-Bin Li¹, Yun-Kun Qi^{2

3}, Qiao-Qiao He², Hua-Song Ai², San-Ling Liu¹, Jia-Xing Wang², Ji-Shen Zheng¹, Lei Liu², Changlin Tian¹

Affiliations

¹ Hefei National Laboratory for Physical Sciences at the Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, China.
² Tsinghua-Peking Center for Life Sciences, Department of Chemistry, Tsinghua University, Beijing 100084, China.
³ School of Pharmacy, Qingdao University, Qingdao, Shandong 266021, China.

No abstract available

Publication types

Letter

MeSH terms

DNA Breaks, Double-Stranded
Histones / metabolism*
Humans
Nucleosomes / metabolism*
Protein Binding
Tumor Suppressor p53-Binding Protein 1 / metabolism*
Ubiquitination

Substances

Histones
Nucleosomes
TP53BP1 protein, human
Tumor Suppressor p53-Binding Protein 1