The PNPLA3 SNP rs738409:G allele is associated with increased liver disease-associated mortality but reduced overall mortality in a population-based cohort

J Hepatol. 2018 Apr;68(4):858-860. doi: 10.1016/j.jhep.2017.11.038. Epub 2017 Dec 11.

Authors

Peter J Meffert¹, Katja D Repp¹, Henry Völzke¹, F Ulrich Weiss², Georg Homuth³, Jens P Kühn⁴, Markus M Lerch⁵, Ali A Aghdassi²

Affiliations

¹ Institute for Community Medicine, University Medicine Greifswald, Germany.
² Department of Medicine A, University Medicine Greifswald, Greifswald, Germany.
³ Institute of Genetics and Functional Genomics, University Medicine Greifswald, Germany.
⁴ Institute of Radiology, University Medicine Greifswald, Germany.
⁵ Department of Medicine A, University Medicine Greifswald, Greifswald, Germany. Electronic address: lerch@uni-greifswald.de.

PMID: 29242079
DOI: 10.1016/j.jhep.2017.11.038

No abstract available

Keywords: Fatty liver disease; Liver-related; Mortality; PNPLA3; Population-based; Study of Health in Pomerania; Variant.

Publication types

Letter
Comment

MeSH terms

Alleles
Hepatitis, Alcoholic*
Homozygote
Humans
Liver
Liver Diseases*