Present and future roles of FDG-PET/CT imaging in the management of gastrointestinal cancer: an update

Nagoya J Med Sci. 2017 Nov;79(4):527-543. doi: 10.18999/nagjms.79.4.527.

Abstract

Positron emission tomography/computed tomography (PET/CT) integrated with 2-[18F]fluoro-2-deoxy-D-glucose (FDG) is a useful tool for acquisition of both glucose metabolism and anatomic imaging data, as only a single device and one diagnostic session is required, thus opening a new field in clinical oncologic imaging. FDG-PET/CT has been successfully used for initial staging, restaging, assessment of early treatment response, evaluation of metastatic disease response, and prognostication of intestinal cancer as well as various malignant tumors. We reviewed the current status and role of FDG-PET/CT for management of patients with esophageal cancer, gastric cancer, and colorectal cancer, with focus on both its usefulness and limitations.

Keywords: colorectal cancer; esophageal cancer; fluorodeoxyglucose (FDG); gastric cancer; positron emission tomography/computed tomography (PET/CT).

Publication types

  • Review

MeSH terms

  • Animals
  • Colorectal Neoplasms / diagnostic imaging
  • Fluorodeoxyglucose F18 / analysis
  • Gastrointestinal Neoplasms / diagnostic imaging*
  • Humans
  • Positron Emission Tomography Computed Tomography / methods*
  • Stomach Neoplasms / diagnostic imaging
  • Tomography, X-Ray Computed / methods*

Substances

  • Fluorodeoxyglucose F18