Intrarectal fixative for positioning of the prostate for intensity modulated radiotherapy

J Cancer Res Ther. 2017 Oct-Dec;13(6):1050-1052. doi: 10.4103/0973-1482.179163.

Abstract

Dose escalation improves local control in carcinoma prostate, but rectal toxicity remains a concern. Various techniques have been there to reduce the dose to the rectum. Mobility of the prostate results in a necessary expansion of the target volume. We describe a new intrarectal fixative, developed in-house with transrectal ultrasonography through the fixative itself for localization of the organ by reporting a case with early carcinoma prostate. Concerns of rectal toxicity limit dose escalation in the treatment of prostate cancer. Intra- and interfraction prostate motion is a concern in dose conformity techniques. The intrarectal fixative system developed in-house physically separates the prostate and rectum during radiation treatment. Thus, both intra- and inter-fractional movement of the organ are addressed, therefore planning target volume expansion can be kept minimal.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Aged
  • Carcinoma / diagnostic imaging
  • Carcinoma / pathology
  • Carcinoma / radiotherapy*
  • Dose Fractionation, Radiation
  • Humans
  • Male
  • Prostate / diagnostic imaging
  • Prostate / pathology
  • Prostate / radiation effects
  • Prostatic Neoplasms / diagnostic imaging
  • Prostatic Neoplasms / pathology
  • Prostatic Neoplasms / radiotherapy*
  • Radiotherapy Dosage
  • Radiotherapy Planning, Computer-Assisted*
  • Radiotherapy, Intensity-Modulated / methods
  • Rectum / diagnostic imaging
  • Rectum / pathology
  • Rectum / radiation effects
  • Tomography, X-Ray Computed