Cholemic or Bile Cast Nephropathy in a Child with Liver Failure

Vikrant Sood; Bikrant B Lal; Suman Lata; Archana Rastogi; Seema Alam

doi:10.1016/j.jceh.2017.05.006

Cholemic or Bile Cast Nephropathy in a Child with Liver Failure

J Clin Exp Hepatol. 2017 Dec;7(4):373-375. doi: 10.1016/j.jceh.2017.05.006. Epub 2017 May 15.

Authors

Vikrant Sood¹, Bikrant B Lal¹, Suman Lata², Archana Rastogi³, Seema Alam¹

Affiliations

¹ Department of Pediatric Hepatology, Institute of Liver and Biliary Sciences, D-1, Vasant Kunj, New Delhi, India.
² Department of Nephrology, Institute of Liver and Biliary Sciences, D-1, Vasant Kunj, New Delhi, India.
³ Department of Pathology, Institute of Liver and Biliary Sciences, D-1, Vasant Kunj, New Delhi, India.

Abstract

Cholemic or bile cast nephropathy is an under-reported entity characterized by acute renal dysfunction in patients with hepatic insult. Limited literature is available regarding its clinical presentation, pathogenesis and prognosis. We hereby present a pediatric case who presented with acute on chronic liver failure with renal dysfunction secondary to cholemic nephropathy.

Keywords: ACLF, acute on chronic liver failure; AKI, acute kidney injury; GCS, Glasgow coma scale; HE, Hematoxylin–Eosin.