The time dependence of a charge accumulation in a 10-15 M albumin solution, flowing through a measuring cell of an analytical flow system injector, had a nonlinear character under certain conditions, within a human physiological temperature range. Sharp charge increases depended on albumin concentration. This effect must be taken into consideration when generating models that describe electrokinetic phenomena in flowing protein solutions and when developing analytical flow systems for the registration of biomolecules in low concentration ranges.
Keywords: analytical flow-through systems; charge accumulation; flowing protein solution; physiological temperature; serum albumin.