Objective: To review and discuss the experience of diagnosis and treatment of adrenal ganglioneuroma. Methods: Clinical data of 80 cases of adrenal ganglioneuroma undergoing surgery during January 1982 to May 2017 at Peking Union Medical College Hospital were retrospectively analyzed. There were 36 male and 44 female patients. Age ranged from 8 to 69 years old (mean 37.7 years old). The tumor diameter were 1.5 to 18.0 cm (mean 4.3 cm). There were 61 cases of adrenal ganglioneuroma diagnosed by imaging examination. All patients underwent adrenalectomy. Results: All procedures were performed successfully without serious complication. Including 15 open surgery and 64 retroperitoneal laparoscopic surgery. One laparoscopic case conversion to open surgery. The pathological diagnosis was adrenal ganglioneuroma. Fifteen cases were mixed with other tumor components. No recurrence or metastasis was observed during the follow-up of 2 months to 35 years. Conclusions: The diagnostic techniques for adrenal ganglioneuroma are helpful to judge the tumor property before operation. The laparoscopic surgery has become the current method for resecting tumors. It shows advantages of small trauma and speedy recovery. The relationship between tumor and surrounding tissues should be understand clearly before operation. Full preparation must be made before operation if adrenal ganglioneuroma mixed with other tumor components.
目的： 总结单中心80例肾上腺节细胞神经瘤的诊疗经验。 方法： 回顾性分析北京协和医院1982年1月至2017年5月收治的80例肾上腺节细胞神经瘤患者的临床资料。男性36例，女性44例。年龄8～69岁，平均37.7岁。肿瘤最大径1.5～18.0 cm，平均4.3 cm。术前影像学诊断考虑肾上腺节细胞神经瘤61例。全部患者接受肾上腺肿瘤切除术。 结果： 所有手术顺利完成，其中开放手术15例，腹腔镜手术64例，腹腔镜中转开放手术1例，无严重手术并发症。80例患者均经术后病理学检查证实为肾上腺节细胞神经瘤，15例患者混合其他肿瘤成分。术后随访2个月至35年，未见肿瘤复发和转移。 结论： 肾上腺节细胞神经瘤的特定影像学表现有助于术前判断肿瘤性质。腹腔镜手术已成为切除肾上腺节细胞神经瘤的主要方法，具有创伤小、恢复快等优点。术前需仔细了解肿瘤与周围组织关系、肿瘤有无其他组成成分，在做好充分准备的前提下完成手术治疗。.
Keywords: Adrenal gland neoplasms; Diagnosis; Laparoscopy.