Bladder Fetal Rhabdomyoma Intermediate Type

Urol Int. 2018;101(2):240-244. doi: 10.1159/000485256. Epub 2017 Dec 8.

Abstract

Introduction: Rhabdomyomas are benign tumors of striated muscle, the bladder localization is very rare.

Clinical case: We present an 87-year-old male consulting for gross hematuria. Cystoscopy was done with evidence of bulged bladder mucosa in right side wall and dome. Post-transurethral resection of the bladder (TURB) pathological anatomy was negative for malignancy. As extension study abdominopelvic computed tomography was performed identifying a bladder thickening of right posterior sidewall and an increased density of the adjacent fat. Second TURB was performed and a fetal bladder rhabdomyoma intermediate type was obtained. We performed another biopsy to confirm this rare pathology, with the same diagnosis. Subsequently, the patient continues with hematuria deciding on hemostatic radiotherapy (not candidate for cystectomy or arterial embolization). Currently, the patient is asymptomatic.

Discussion: Bladder rhabdomyomas are rare tumors, and, in fact, there have been only 5 papers published. Some cases are only isolation cited in the bladder mesenchymal tumors, and other polemic cases in which clinical and macroscopic characteristics remembered a rhabdomyosarcoma. The importance of this publication case is the macro- and microscopic images that can corroborate the final diagnosis, helping us to differentiate between rhabdomyoma, rhabdomyofibroma, or the malignant rhabdomyosarcoma, and shows the treatment possibilities of these tumors.

Keywords: Radical cystectomy; Bladder tumor; Hematuria; Radiotherapy; Rhabdomyoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged, 80 and over
  • Biomarkers, Tumor / analysis
  • Biopsy
  • Desmin / analysis
  • Humans
  • Immunohistochemistry
  • Male
  • Myogenin / analysis
  • Rhabdomyoma / chemistry
  • Rhabdomyoma / diagnostic imaging
  • Rhabdomyoma / pathology*
  • Rhabdomyoma / surgery
  • Tomography, X-Ray Computed
  • Ultrasonography
  • Urinary Bladder Neoplasms / chemistry
  • Urinary Bladder Neoplasms / diagnostic imaging
  • Urinary Bladder Neoplasms / pathology*
  • Urinary Bladder Neoplasms / surgery

Substances

  • Biomarkers, Tumor
  • Desmin
  • MYOG protein, human
  • Myogenin