From Commensal to Consumer: Staphylococcus aureus Toxins, Diseases, and Detection Methods

Angela T Nguyen; Sandra M Tallent

doi:10.5740/jaoacint.17-0366

From Commensal to Consumer: Staphylococcus aureus Toxins, Diseases, and Detection Methods

J AOAC Int. 2018 Jul 1;101(4):1127-1134. doi: 10.5740/jaoacint.17-0366. Epub 2017 Dec 8.

Authors

Angela T Nguyen¹, Sandra M Tallent¹

Affiliation

¹ U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, 5001 Campus Dr, College Park, MD 20740, USA.

PMID: 29216934
DOI: 10.5740/jaoacint.17-0366

Abstract

Staphylococcus aureus is a Gram-positive bacterium capable of causing a wide array of infections. Generally a commensal organism, S. aureus encodes several virulence mechanisms that contribute to disease progression. This review highlights toxins as a secreted virulence factor by S. aureus, the diseases that manifest as a result, and the methods used to detect them. In particular, the advantages and limitations of current toxin detection methods are discussed.

Publication types

Review

MeSH terms

Bacterial Toxins / analysis
Bacterial Toxins / metabolism
Disease Reservoirs
Humans
Immunoassay / methods
Staphylococcal Food Poisoning / epidemiology
Staphylococcal Food Poisoning / microbiology
Staphylococcal Infections / epidemiology*
Staphylococcal Infections / microbiology
Staphylococcus aureus / pathogenicity*
Toxins, Biological / analysis*
Toxins, Biological / metabolism
Virulence Factors

Substances

Bacterial Toxins
Staphylococcal pyrogenic exotoxin C
Toxins, Biological
Virulence Factors