Nonbacterial thrombotic endocarditis involving all four cardiac valves

Sachiko Kawada; Mitsuhito Kuriyama; Yasuhiro Kotani; Shou Tsushima; Atsushi Tanabe; Yukio Kioka

doi:10.1177/0218492317748091

Nonbacterial thrombotic endocarditis involving all four cardiac valves

Asian Cardiovasc Thorac Ann. 2018 Jan;26(1):44-46. doi: 10.1177/0218492317748091. Epub 2017 Dec 6.

Authors

Sachiko Kawada¹, Mitsuhito Kuriyama¹, Yasuhiro Kotani², Shou Tsushima³, Atsushi Tanabe¹, Yukio Kioka¹

Affiliations

¹ 1 Department of Cardiovascular Surgery, Cardiovascular Centre, 13757 Fukuyama City Hospital , Hiroshima, Japan.
² 2 Department of Cardiovascular Surgery, Okayama University Hospital, Okayama, Japan.
³ 3 Department of Cardiovascular Internal Medicine, Cardiovascular Centre, Fukuyama City Hospital, Hiroshima, Japan.

PMID: 29212343
DOI: 10.1177/0218492317748091

Abstract

This report describes a case of nonbacterial thrombotic endocarditis caused by Waldenström macroglobulinemia, with diffuse endocardial lesions and involvement of all 4 cardiac valves. A 77-year-old man presented with heart failure due to severe regurgitation of all 4 cardiac valves; surgical repair using bioprosthetic valves was indicated. A pathological study revealed fibrin-triggered thrombus formation that confirmed the diagnosis of nonbacterial thrombotic endocarditis. In cases of nonbacterial thrombotic endocarditis, the underlying cause should be investigated.

Keywords: Endocarditis; Heart valve prosthesis implantation; Heart valves; Thrombophilia; Thrombosis; Waldenstrom macroglobulinemia.

Publication types

Case Reports

MeSH terms

Aged
Aortic Valve Insufficiency / diagnostic imaging
Aortic Valve Insufficiency / etiology*
Aortic Valve Insufficiency / surgery
Autopsy
Bioprosthesis
Biopsy
Bone Marrow Examination
Echocardiography, Transesophageal
Endocarditis, Non-Infective / diagnostic imaging
Endocarditis, Non-Infective / etiology*
Endocarditis, Non-Infective / surgery
Fatal Outcome
Heart Valve Prosthesis
Heart Valve Prosthesis Implantation / instrumentation
Humans
Male
Mitral Valve Insufficiency / diagnostic imaging
Mitral Valve Insufficiency / etiology*
Mitral Valve Insufficiency / surgery
Pulmonary Valve Insufficiency / diagnostic imaging
Pulmonary Valve Insufficiency / etiology*
Pulmonary Valve Insufficiency / surgery
Thrombosis / diagnostic imaging
Thrombosis / etiology*
Thrombosis / surgery
Treatment Outcome
Tricuspid Valve Insufficiency / diagnostic imaging
Tricuspid Valve Insufficiency / etiology*
Tricuspid Valve Insufficiency / surgery
Waldenstrom Macroglobulinemia / complications*
Waldenstrom Macroglobulinemia / diagnosis