Granulomatosis With Polyangiitis in a Young Adult With Down Syndrome: Therapeutic Challenges and Clues to Immunopathogenesis

MeSH terms

• Acute Kidney Injury / diagnosis
• Acute Kidney Injury / etiology
• Acute Kidney Injury / therapy
• Adult
• Antibodies, Antineutrophil Cytoplasmic / blood*
• Biopsy / methods
• Blood Transfusion / methods
• Diagnosis, Differential
• Down Syndrome* / complications
• Down Syndrome* / immunology
• Glucocorticoids / administration & dosage*
• Granulomatosis with Polyangiitis* / complications
• Granulomatosis with Polyangiitis* / immunology
• Granulomatosis with Polyangiitis* / physiopathology
• Granulomatosis with Polyangiitis* / therapy
• Hemoptysis* / diagnosis
• Hemoptysis* / etiology
• Hemoptysis* / therapy
• Humans
• Immunoglobulins, Intravenous / administration & dosage*
• Immunologic Factors / administration & dosage
• Kidney / pathology
• Male
• Patient Care Management / methods
• Patient Selection
• Respiration, Artificial / methods
• Respiratory Insufficiency* / diagnosis
• Respiratory Insufficiency* / etiology
• Respiratory Insufficiency* / therapy
• Rituximab / administration & dosage*
• Tomography, X-Ray Computed / methods
• Treatment Outcome