Role of Activin A in the Pathogenesis of Endothelial Cell Dysfunction in Preeclampsia

Methods Mol Biol. 2018:1710:39-52. doi: 10.1007/978-1-4939-7498-6_4.

Abstract

This chapter describes the methodologies which may be used in evaluating in vitro endothelial cell dysfunction in preeclampsia.

Keywords: Activin A; Endothelial function; Endothelin; Follistatin; ICAM-1; Preeclampsia; VCAM-1.

MeSH terms

  • Activins / analysis
  • Cells, Cultured
  • Endothelial Cells / pathology*
  • Endothelin-1 / analysis
  • Enzyme-Linked Immunosorbent Assay / methods
  • Female
  • Follistatin / analysis
  • Human Umbilical Vein Endothelial Cells
  • Humans
  • Intercellular Adhesion Molecule-1 / analysis
  • Pre-Eclampsia / pathology*
  • Pregnancy
  • Radioimmunoassay / methods
  • Vascular Cell Adhesion Molecule-1 / analysis

Substances

  • Endothelin-1
  • Follistatin
  • Vascular Cell Adhesion Molecule-1
  • activin A
  • Activins
  • Intercellular Adhesion Molecule-1