Cardiovascular disease is the main threat to human health, which is one of the important causes of death in worldwide. N-methyl-D-aspartate receptor (NMDAR) is one of crucial ionic glutamate receptors. The physiology and pharmacology function of the composition of NMDAR are very complicated. Researches have shown that NMDAR with a high permeability to calcium and a unique feature of controlling numerous calcium-dependent processes. NMDAR affects the occurrence and development of cardiovascular disease such as hypertension, arrhythmia, myocardial infarction.
心血管疾病是人类健康的主要威胁，同时也是全世界范围内导致死亡的主要原因之一。N-甲基-D-天冬氨酸受体(N-methyl-D-aspartic acid receptor，NMDAR)是一种重要的离子型谷氨酸受体，其组成亚单位的生理学和药理学功能都很复杂。NMDAR对钙离子高度渗透，控制许多与钙相关的生理过程。NMDAR参与高血压、心律失常、心肌梗死等心血管疾病的发生与发展过程。.