The genus Gentiana comprises approximately 400 species. Many species have a wide range of pharmacological activities and have been used therapeutically for thousands of years. To provide comprehensive guidance, utilization and quality control of Gentiana species, this review presents updated information concerning the recent application and progress of chemical analysis including phytochemical analysis, sample preparation and chemometrics. Detailed and comprehensive data including number of analytes, extraction/separation methods, analytical techniques and chemometrics are shown as corresponding tables. These data illustrate that the development of newly discovered compounds and therapeutic uses, understanding of the structure-activity relationship and establishment of harmonious and effective medicinal herb standards are the direction of advancement in future research.
Keywords: Gentiana; chemometrics; chromatographic techniques; quality control; spectroscopy.