Ambient Air Pollution and Biomarkers of Health Effect

Adv Exp Med Biol. 2017:1017:59-102. doi: 10.1007/978-981-10-5657-4_4.

Abstract

Recently, the air pollution situation of our country is very serious along with the development of urbanization and industrialization. Studies indicate that the exposure of air pollution can cause a rise of incidence and mortality of many diseases, such as chronic obstructive pulmonary disease (COPD), asthma, myocardial infarction, and so on. However, there is now growing evidence showing that significant air pollution exposures are associated with early biomarkers in various systems of the body. In order to better prevent and control the damage effect of air pollution, this article summarizes comprehensively epidemiological studies about the bad effects on the biomarkers of respiratory system, cardiovascular system, and genetic and epigenetic system exposure to ambient air pollution.

Keywords: Air pollution; Epigenetic; Genetic; Inflammation; Oxidative stress.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Air Pollutants / adverse effects
  • Air Pollutants / analysis*
  • Air Pollution / adverse effects
  • Air Pollution / analysis*
  • Biomarkers / metabolism*
  • Cardiovascular Diseases / diagnosis*
  • Cardiovascular Diseases / epidemiology
  • Cardiovascular Diseases / genetics
  • Cardiovascular Diseases / metabolism
  • China / epidemiology
  • DNA Damage
  • Environmental Exposure* / adverse effects
  • Environmental Monitoring / methods*
  • Genetic Markers
  • Health Status
  • Humans
  • Inflammation Mediators / metabolism
  • Oxidative Stress
  • Particulate Matter / adverse effects
  • Particulate Matter / analysis*
  • Protein Carbonylation
  • Public Health*
  • Respiratory Tract Diseases / diagnosis*
  • Respiratory Tract Diseases / epidemiology
  • Respiratory Tract Diseases / genetics
  • Respiratory Tract Diseases / metabolism
  • Risk Assessment

Substances

  • Air Pollutants
  • Biomarkers
  • Genetic Markers
  • Inflammation Mediators
  • Particulate Matter