Fibrodysplasia ossificans progressiva in China

Dunmin She; Keqin Zhang

doi:10.1016/j.bone.2017.11.016

Fibrodysplasia ossificans progressiva in China

Bone. 2018 Apr:109:101-103. doi: 10.1016/j.bone.2017.11.016. Epub 2017 Nov 22.

Authors

Dunmin She¹, Keqin Zhang²

Affiliations

¹ Department of Endocrinology and Metabolism, Tongji Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China.
² Department of Endocrinology and Metabolism, Tongji Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China. Electronic address: keqzhang2007@126.com.

PMID: 29175272
DOI: 10.1016/j.bone.2017.11.016

Abstract

Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare and devastating disorder characterized by cumulative episodes of progressive heterotopic ossification. It is estimated that there exist 600-700 patients in Mainland China. Nevertheless, due to the rarity, many FOP patients were initially misdiagnosed. Until now fewer than 150 patients have been identified in Mainland China. This review summarizes the epidemiology and clinical features of FOP patients, the progress of clinical and basic research in China, and the future of FOP care in China.

Keywords: China; Diagnosis; Epidemiology; Fibrodysplasia ossificans progressiva; Research.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
China / epidemiology
Disease Progression
Humans
Myositis Ossificans / diagnosis*
Myositis Ossificans / epidemiology*