The Natural History of Degenerative Cervical Myelopathy

Neurosurg Clin N Am. 2018 Jan;29(1):21-32. doi: 10.1016/j.nec.2017.09.002. Epub 2017 Oct 27.

Abstract

Despite being the leading cause of spinal cord dysfunction among adults worldwide, little is known about the natural history of degenerative cervical myelopathy (DCM). There is mounting evidence of the effectiveness of surgery for DCM in halting progression of symptoms, and in fact, in improving neurologic outcomes, functional status, and quality of life. However, surgical decision making relies on a weighing of the risks and benefits of alternative strategies. We reviewed the available literature pertaining to the natural course of DCM and the predictors of outcome of nonoperative approaches.

Keywords: Cervical spondylotic myelopathy; Degenerative cervical myelopathy; Natural history; Outcomes; Spinal cord; Spine surgery.

Publication types

  • Review

MeSH terms

  • Cervical Vertebrae / pathology*
  • Cervical Vertebrae / surgery
  • Decompression, Surgical
  • Disease Progression
  • Humans
  • Quality of Life
  • Spinal Cord Compression / etiology
  • Spinal Cord Compression / pathology*
  • Spinal Cord Compression / surgery
  • Spondylosis / complications
  • Spondylosis / pathology*
  • Spondylosis / surgery