Developing an adherence in hypertension questionnaire short version: MUAH-16

J Clin Hypertens (Greenwich). 2018 Jan;20(1):118-124. doi: 10.1111/jch.13137. Epub 2017 Nov 24.

Abstract

The Maastricht Utrecht Adherence in Hypertension (MUAH) questionnaire provides clinicians with information about the causes of a patient's poor adherence to antihypertensive drugs. In this study, the authors aimed to develop and validate a short version of the MUAH questionnaire. After an exploratory factor analysis, the number of MUAH items was reduced. The original MUAH questionnaire (model 1) was compared with the 16-item MUAH short version (model 2). Next, this short version of MUAH (MUAH-16) with all factors correlated (model 2a) was compared with the short version of MUAH with four subscales that contribute to a global factor of adherence (model 2b). Model 1 had a poor fit to the data (χ2 269 = 663.41, P < .001, comparative fit index = 0.695, root mean square error of approximation = 0.06), and model 2 had a very good fit to the data (χ2 100 = 171.07, P < .001, comparative fit index = 0.92, root mean square error of approximation = 0.04). When comparing model 2a with model 2b, the chi-square difference of the model (Δχ2 2 = 4.06; P = .067) revealed that the fits of both models were not significantly different. These findings suggest that MUAH-16 better represents a patient's adherence to antihypertensive medication than the original MUAH questionnaire.

Keywords: patient adherence; patient education; questionnaires.

MeSH terms

  • Antihypertensive Agents / therapeutic use*
  • Cross-Sectional Studies
  • Factor Analysis, Statistical
  • Humans
  • Hypertension* / drug therapy
  • Hypertension* / epidemiology
  • Hypertension* / psychology
  • Patient Compliance* / psychology
  • Patient Compliance* / statistics & numerical data
  • Portugal / epidemiology
  • Quality of Life*
  • Reproducibility of Results
  • Surveys and Questionnaires*

Substances

  • Antihypertensive Agents