Effects of exposure to electromagnetic field from 915 MHz radiofrequency identification system on circulating blood cells in the healthy adult rat

Bioelectromagnetics. 2018 Jan;39(1):68-76. doi: 10.1002/bem.22093. Epub 2017 Nov 24.

Abstract

We investigated whether exposure to the 915 MHz radiofrequency identification (RFID) signal affected circulating blood cells in rats. Sprague-Dawley rats were exposed to RFID at a whole-body specific absorption rate of 2 W/kg for 8 h per day, 5 days per week, for 2 weeks. Complete blood counts were performed after RFID exposure, and the CD4+ /CD8+ ratio was determined by flow cytometry. The number of red blood cells (RBCs) and the values of hemoglobin, hematocrit, and RBC indices were increased in the RFID-exposed group compared with those in the cage-control and sham-exposed groups (P < 0.05). However, the RBCs and platelet numbers were within normal physiologic response ranges. The number of white blood cells, including lymphocytes, was decreased in RFID-exposed rats. However, there was no statistically significant difference between the sham-exposed and RFID-exposed groups in terms of T-cell counts or CD4+ /CD8+ ratio (P > 0.05). Although the number of circulating blood cells was significantly altered by RFID exposure at a whole-body specific absorption rate of 2 W/kg for 2 weeks, these changes do not necessarily indicate that RFID exposure is harmful, as they were within the normal physiological response range. Bioelectromagnetics. 39:68-76, 2018. © 2017 Wiley Periodicals, Inc.

Keywords: 915 MHz RFID; CD4/CD8 ratio; Sprague-Dawley; blood cells; rats.

MeSH terms

  • Animals
  • Blood Cells / cytology
  • Blood Cells / radiation effects*
  • CD4-Positive T-Lymphocytes / cytology
  • CD4-Positive T-Lymphocytes / radiation effects
  • CD8-Positive T-Lymphocytes / cytology
  • CD8-Positive T-Lymphocytes / radiation effects
  • Cell Count
  • Electromagnetic Fields / adverse effects*
  • Erythrocytes / cytology
  • Erythrocytes / radiation effects
  • Male
  • Radio Frequency Identification Device*
  • Rats
  • Rats, Sprague-Dawley
  • Whole-Body Irradiation / adverse effects