Cellular adhesion: Instant integrin mechanosensing

Ning Wang

doi:10.1038/nmat5041

Cellular adhesion: Instant integrin mechanosensing

Nat Mater. 2017 Nov 24;16(12):1173-1174. doi: 10.1038/nmat5041.

Author

Ning Wang¹

Affiliation

¹ Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China, and the Department of Mechanical Science and Engineering, College of Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.

Abstract

Single-cell force spectroscopy reveals rapid, biphasic integrin activation and reinforcement of cell-matrix bonds during the initial steps of fibroblast adhesion.

Publication types

Comment

MeSH terms

Cell Adhesion
Fibronectins
Integrin alpha5beta1*
Integrins*
Mechanotransduction, Cellular

Substances

Fibronectins
Integrin alpha5beta1
Integrins

Grants and funding

R01 GM072744/GM/NIGMS NIH HHS/United States