Biological therapies in psoriasis - revisited

Rom J Intern Med. 2018 Jun 1;56(2):75-84. doi: 10.1515/rjim-2017-0045.

Abstract

Psoriasis is a chronic, immune mediated disorder affecting approximately 2% of the population. Even in our days, patients with psoriasis are confronted with stigmatization and social rejection. As a result, their quality of life is significantly impaired. Biological therapies have revolutionized the treatment of moderate to severe psoriasis. The aim of this paper is to look over the most important biological therapies available for the management of plaque-type psoriasis.

Keywords: IL-17; TNF-α; anti-IL-12/23; biological therapies; psoriasis.

Publication types

  • Review

MeSH terms

  • Biological Factors / therapeutic use*
  • Humans
  • Psoriasis / psychology
  • Psoriasis / therapy*
  • Quality of Life
  • Social Stigma

Substances

  • Biological Factors