The Trajectory of Anhedonic and Depressive Symptoms in Anorexia Nervosa: A Longitudinal and Cross-Sectional Approach

Eur Eat Disord Rev. 2018 Jan;26(1):69-74. doi: 10.1002/erv.2565. Epub 2017 Nov 23.

Abstract

Anhedonia, the inability to experience pleasure, is associated with depression, schizophrenia and also anorexia nervosa (AN). However, it remains unanswered whether anhedonic symptoms in AN are undernutrition-dependent depressive symptoms or a core feature of AN. Therefore, we aim at investigating the trajectory of anhedonic and depressive symptoms over the course of the disorder. Self-reported symptoms were collected in 35 nonmedicated acutely ill, 33 long-term recovered patients and 62 healthy females. The majority of the acutely ill (n = 24) were followed up after >15% weight restoration (short-term recovery). Anhedonia was found to be increased during the acute, short-term as well as long-term recovered state while depressive symptoms showed a reduction over time. Additionally, depressive symptoms were negatively associated with body mass index in acute patients. This provides evidence of anhedonia being a trait-characteristic of AN, relatively unrelated to undernutrition-dependent depressive symptoms. Results are discussed with regard to implications for treatment and prevention. Copyright © 2017 John Wiley & Sons, Ltd and Eating Disorders Association.

Keywords: anhedonia; anorexia nervosa; depressive symptoms; longitudinal; undernutrition.

MeSH terms

  • Adolescent
  • Adult
  • Anhedonia*
  • Anorexia Nervosa / psychology*
  • Anorexia Nervosa / therapy
  • Case-Control Studies
  • Child
  • Cross-Sectional Studies
  • Depression / psychology*
  • Female
  • Humans
  • Longitudinal Studies
  • Self Report
  • Young Adult